Skinoren (azelaic Acid): medication for acne treatment and prophylaxis

Skinoren (azelaic Acid): medication for acne treatment and prophylaxis

In spite of many scientific investigations and the discovery of new medicines, the successful acne treatment remains the difficult task. Acne vulgaris occurs in 80-90% of all teenagers in pubertal age. Usually the acne manifestations are decreased to 20-30 years; however in some cases (hormonal dysfunction) acne may affect people even in 30-40 years.

The causes of acne are currently well-known. These are: increased production of skin fat, hyperkeratosis of oil glands passages, multiplication of Propionibacterium acnes and inflammation. Successful acne treatment is based on the pathogeneses and severity of the disease. In mild and moderate cases of acne, medicines for the topical application (gels, creams, lotions) are used. Oral antibiotics (tetracycline, doxicycyline), retinoids(Roaccutane), anti androgen medicines(Diane 35, Androcur) are indicated only in severe cases.

While the scientific investigations some researches paid attention to azelaic acid that what used in hyperpigmentation. Clinical trials showed that Azelaic acid is highly effective in hyperpigmentation and melanotic cancer without affecting healthy skin cells. Azelaic acid penetrates into melanoma, carcinoma, lymphoma cells possessing antiproliferative and cytostatic action. Further investigations showed that Azelaic acid is effective in acne treatment as well. As a result a new topical medication under the brand name Skinoren was released on the pharmaceutical market.

Azelaic acid is a natural compound that is contained in the urine in small amounts. It’s very important that azelaic acid is not metabolized in toxic substances. That’s why Skinoren bacame one of the most safe and tolerable anti acne medicines.
Skinoren possesses a broad spectrum of the therapeutic activity. It inhibits a range of enzymes that desoxydate oxygen.

Skinoren neutralizes free radicals, exerting anti-oxidative properties. It restores functions of oil glands and hair follicle and retards the replication of Propionibacterium acnes .
Antibacterial and antifungal properties make the medication irreplaceable in acne treatment. Combination of antibacterial, anti-inflammatory and antiproliferative properties acts on the main pathogenesis segments. Skinoren significantly reduces the amount of inflamed and non-inflamed pimples. It acts on superficial papula as well as deep wounds: keloids (cheloid) and cystic lesions. Clinical improvements are observed in 1 month after beginning the therapy with Sinoren, pronounced effect in 4 month and full recovery in 6 month. Thus, effective acne treatment requires time and appropriate application.

Skinoren does not cause systemic side effects. Local manifestations that occur in the beginning of therapy where not significant and pass away in a few days. Skinoren can be used as monotherapy in light and moderate acne or in combination with antibiotics and retinoids in severe acne.
The discovery of Skinoren made possible to open a new chapter in acne treatment. Exactly high efficiency, expressive therapeutic effect and good tolerance made the medication so popular among all anti acne products.

In spite of many scientific investigations and the discovery of new medicines, the successful acne treatment remains the difficult task. Acne vulgaris occurs in 80-90% of all teenagers in pubertal age. Usually the acne manifestations are decreased to 20-30 years; however in some cases (hormonal dysfunction) acne may affect people even in 30-40 years.

The causes of acne are currently well-known. These are: increased production of skin fat, hyperkeratosis of oil glands passages, multiplication of Propionibacterium acnes and inflammation. Successful acne treatment is based on the pathogeneses and severity of the disease. In mild and moderate cases of acne, medicines for the topical application (gels, creams, lotions) are used. Oral antibiotics (tetracycline, doxicycyline), retinoids(Roaccutane), anti androgen medicines(Diane 35, Androcur) are indicated only in severe cases.

While the scientific investigations some researches paid attention to azelaic acid that what used in hyperpigmentation. Clinical trials showed that Azelaic acid is highly effective in hyperpigmentation and melanotic cancer without affecting healthy skin cells. Azelaic acid penetrates into melanoma, carcinoma, lymphoma cells possessing antiproliferative and cytostatic action. Further investigations showed that Azelaic acid is effective in acne treatment as well. As a result a new topical medication under the brand name Skinoren was released on the pharmaceutical market.

Azelaic acid is a natural compound that is contained in the urine in small amounts. It’s very important that azelaic acid is not metabolized in toxic substances. That’s why Skinoren bacame one of the most safe and tolerable anti acne medicines.
Skinoren possesses a broad spectrum of the therapeutic activity. It inhibits a range of enzymes that desoxydate oxygen.

Skinoren neutralizes free radicals, exerting anti-oxidative properties. It restores functions of oil glands and hair follicle and retards the replication of Propionibacterium acnes .
Antibacterial and antifungal properties make the medication irreplaceable in acne treatment. Combination of antibacterial, anti-inflammatory and antiproliferative properties acts on the main pathogenesis segments. Skinoren significantly reduces the amount of inflamed and non-inflamed pimples. It acts on superficial papula as well as deep wounds: keloids (cheloid) and cystic lesions. Clinical improvements are observed in 1 month after beginning the therapy with Sinoren, pronounced effect in 4 month and full recovery in 6 month. Thus, effective acne treatment requires time and appropriate application.
Skinoren does not cause systemic side effects. Local manifestations that occur in the beginning of therapy where not significant and pass away in a few days. Skinoren can be used as monotherapy in light and moderate acne or in combination with antibiotics and retinoids in severe acne.

The discovery of Skinoren made possible to open a new chapter in acne treatment. Exactly high efficiency, expressive therapeutic effect and good tolerance made the medication so popular among all anti acne products.